9,991 research outputs found

    POFGEN: a design automation system for VLSI digital filters with invariant transfer function

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    Managing quality assurance and enhancement processes in higher education with special reference to initial teacher training provision

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    My intention in carrying out this project was to examine the relevance of developing refined approaches toward quality assurance in order to accommodate external demand under a common system. Each area of critical analysis established sources of conflict of interest amongst academics in the School and provided an indication of the way in which these might be resolved. The academic provision in the School is diverse and is subject to external scrutiny through the Quality Assurance Agency (QAA) and Teacher Training Agency (TTA) the latter of whom works alongside the Office for Standards in Teacher Education, OfSTED. Throughout this time the University has operated an internal quality assurance and enhancement process based on the QAA quality assurance methodology whereas Initial Teacher Training programmes within the School have been subject to the inspection methodology of OfSTED. Three areas of critical analysis formed the basis of my research methodology conducted through case study and primary document analysis. The self assessment document is a product of QAA demand and contrasts with OfSTED inspection demand, the subject specification raises questions about knowledge and its control in higher education when compared with the TTA Standards for the Award of Qualified Teacher Status, and the School Annual Monitoring Report represents the internal dichotomy of demand that sometimes exists for members of academic staff who engage in the process of writing such reports. My main finding suggests that the 'self imposed burden' of quality assurance can be reduced within the University and School in order to facilitate a more coherent and effective QA process

    Robust image and video coding with pyramid vector quantisation

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    A high throughput adaptive DFE for HIPERLAN

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    Rotationally invariant texture features using the dual-tree complex wavelet transform

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    Contradictions in social enterprise: do they draw in straight lines or circles?

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    This paper provides a critical perspective on the discourse surrounding the concept of social enterprise. The paper shifts the lens away from numbers to consider how actors see themselves as social enterprises. The authors make sense of the foundations upon which the concept of social enterprise and entrepreneurship is ‘drawn’ – quite literally – by considering linear models and diagrams that analyse social enterprise on a continuum between non-profit (mission) and profit (market) orientation. A great deal has been made of the success and growth of social enterprise. The imagery in the literature reflects an emphasis on growth resulting from ‘the rising tide of commercialisation of non-profit organisations’ (Dees, 1998) with the result that the CBI now includes over 50,000 organisations in a social enterprise sector (SBS, 2005). Despite reports of rapid growth, there is awareness that ‘take-up of social enterprise model … is patchy and fails to reflect the enthusiasm with which it is discussed’ (Stevenson in Westall &amp; Chalkley 2007). We ask why? A methodological approach involving visual drawings by actors reveals stories and sensemaking experiences of social enterprises. Open conversations enabled the researchers to gain deep insights that would not have been as insightful through a quantitative approach. The key findings suggest: Firstly, participants report tensions when pursuing social and economic goals simultaneously. Secondly, whilst some welcome opportunities that are emerging, others perceive substantive threats to the third sector. Thirdly, Social enterprise emerges as a diverse and heterogeneous movement located at the boundaries of public, private and voluntary sectors. At each boundary, different constitutional forms and practices are seen. In conclusion, it is argued that the linear perspective itself gives the impression that there is a ‘patchy’ take up of social enterprise. A heterogeneous perspective reveals that theory and policy development is patchy, rather than social enterprise practices. The unique contribution this research paper offers is within the depth of enquiry and insight into the actual practices provided from those within the field. The critical perspective is taken from the literature and discussed in the settings of the actors in the field which provides practitioners, business support agencies and academics with a different level of empirical investigation that captures an originality and narrative that has barely been explored before.</p

    A rhodanine agent active against non-replicating intracellular Mycobacterium avium subspecies paratuberculosis.

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    BACKGROUND: Antibiotic therapy targeting chronic mycobacterial disease is often ineffective due to problems with the emergence of drug resistance and non-replicating persistent intracellular antibiotic resistant phenotypes. Strategies which include agents able to enhance host cell killing mechanisms could represent an alternative to conventional methods with the potential for host clearance if active against dormant phenotypes. Investigations of agents with potential activity against non-replicating mycobacteria however are restricted due to a need for assays that can assess bacterial viability without having to culture. RESULTS: This study describes the development and use of a pre16S ribosomal gene RNA/DNA ratio viability assay which is independent of the need for culture, supported by a novel thin layer accelerated mycobacterial colony forming method for determining viability and culturability of MAP in intracellular environments. We describe the use of these tools to demonstrate intracellular killing activity of a novel rhodanine agent (D157070) against the intracellular pathogen Mycobacterium avium subspecies paratuberculosis (MAP) and show that the culturability of MAP decreases relative to its viability on intracellular entry suggesting the induction of a non-culturable phenotype. We further demonstrate that D157070, although having no direct activity against the culturability of extracellular MAP, can bind to cultured MAP cells and has significant influence on the MAP transcriptome, particularly with respect of delta(L )associated genes. D157070 is shown to be taken up by bovine and human cells and able to enhance host cell killing, as measured by significant decreases in both culturability and viability of intracellular MAP. CONCLUSIONS: This work suggests that pre16srRNA gene ratios represent a viable method for studying MAP viability. In addition, the rhodanine agent D157070 tested is non-toxic and enhances cell killing activity against both growing and latent MAP phenotypes

    Localisation of mobile nodes in wireless networks with correlated in time measurement noise.

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    Wireless sensor networks are an inherent part of decision making, object tracking and location awareness systems. This work is focused on simultaneous localisation of mobile nodes based on received signal strength indicators (RSSIs) with correlated in time measurement noises. Two approaches to deal with the correlated measurement noises are proposed in the framework of auxiliary particle filtering: with a noise augmented state vector and the second approach implements noise decorrelation. The performance of the two proposed multi model auxiliary particle filters (MM AUX-PFs) is validated over simulated and real RSSIs and high localisation accuracy is demonstrated

    Seeing social enterprise through the theoretical conceptualisation of ethical capital

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    Objectives: Current conceptualisations of social enterprise fail to fully satisfy an understanding of the movement. A focus on the economic implies a business model where deep tensions lie. A focus on social capital offers a different frame of reference, yet both these conceptualisations fail to fully identify the phenomena that is social enterprise. The objective of this paper seeks to fill that gap. Ethical capital is offered here as the missing conceptualisation in the field of social enterprise. Prior work: Pearce (2003) describes social enterprises as part of the third system, closer to the first system (private business), than the second system (public provision), yet primarily social and secondly a business. Social Enterprises are described as trading organisations in a market (Pearce 2003). A focus and operationalisation for social enterprises to be ‘business-like’ and ‘entrepreneurial’ is well documented (Leadbeater 1997; Dees 1998; Nicholls 2006b). Approach: Yet, if as part of the third sector, social enterprises are as Dart (2004) suggests; ‘blurring the boundaries between non-profit and profit’, but what blurs? What is compromised? What exactly is lost (or gained)? What challenges are there for social enterprises? And is a managerialist ideology taking precedence over the social? This paper provides a conceptual paper that seeks to outline the arguments on the table and develop an ethical capital conceptualisation of social enterprise. Results: This paper very much aims at starting the process of intellectual debate about the notion of ethical capital in social enterprises. The conclusions of this paper outline further research questions that need to be addressed in order to fully develop this concept. Implications: The current ideology of the neo-classical economic paradigm it is argued in the paper pursues interests towards the self and towards the erosion of the moral basis of association. The outcome leaves society with a problem of low ethical virtue - the implications of this paper are that social enterprises maximise ethical virtue beyond any other form of organisation and as such hold great value beyond their missions and values. Value: This paper offers great value in the understanding of social enterprise through fresh insight into the conceptualisation. A critical perspective to the current literature is taken and discussed but though the introduction of ethical capital this paper takes our understanding of the value of the sector into another light, providing practitioners, business support agencies and academics alike with a different level of conceptualisation that has not been explored before.</p
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